{"id":72257,"date":"2025-03-06T03:13:29","date_gmt":"2025-03-06T08:13:29","guid":{"rendered":"https:\/\/www.lintyco.com\/?p=72257"},"modified":"2026-07-08T23:12:21","modified_gmt":"2026-07-09T03:12:21","slug":"comprehensive-guide-to-pharmaceutical-blister-packaging-materials-equipment-and-process","status":"publish","type":"post","link":"https:\/\/www.lintyco.com\/vi\/comprehensive-guide-to-pharmaceutical-blister-packaging-materials-equipment-and-process\/","title":{"rendered":"H\u01b0\u1edbng d\u1eabn to\u00e0n di\u1ec7n v\u1ec1 \u0111\u00f3ng g\u00f3i v\u1ec9 thu\u1ed1c: V\u1eadt li\u1ec7u, thi\u1ebft b\u1ecb v\u00e0 quy tr\u00ecnh"},"content":{"rendered":"<p>Blister packaging plays a crucial role in protecting medications from environmental factors such as moisture, light, and air, ensuring their safety, potency, and effectiveness. This packaging method is widely used for tablets, capsules, and suppositories due to its ability to provide reliable protection, ease of use, and extended shelf life.<\/p>\n\n\n\n<p>Whether you are new to the industry or looking to refine your packaging knowledge, understanding these essential components is vital to maintaining the integrity and safety of pharmaceutical products.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">V\u1eadt li\u1ec7u \u0111\u00f3ng g\u00f3i v\u1ec9<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>V\u1eadt li\u1ec7u d\u00f9ng \u0111\u1ec3 \u0111\u00f3ng g\u00f3i v\u1ec9 thu\u1ed1c c\u1ee7a m\u00e1y \u0111\u00f3ng g\u00f3i v\u1ec9 thu\u1ed1c ch\u1ee7 y\u1ebfu bao g\u1ed3m t\u1ea5m nh\u1ef1a, v\u1eadt li\u1ec7u n\u1ec1n, v\u1eadt li\u1ec7u ph\u1ee7 nhi\u1ec7t v\u00e0 m\u1ef1c in n\u1ec1n.<br><strong>(1) V\u1eadt li\u1ec7u t\u1ea5m nh\u1ef1a<\/strong><\/p>\n\n\n\n<p>T\u1ea5m nh\u1ef1a c\u1ee9ng th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111\u00f3ng g\u00f3i v\u1ec9 c\u1ee7a m\u00e1y \u0111\u00f3ng g\u00f3i v\u1ec9 d\u01b0\u1ee3c ph\u1ea9m ch\u1ee7 y\u1ebfu bao g\u1ed3m polyvinyl clorua, polyvinylidene clorua v\u00e0 m\u1ed9t s\u1ed1 v\u1eadt li\u1ec7u composite. Hi\u1ec7n nay, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i nh\u1ea5t l\u00e0 t\u1ea5m nh\u1ef1a c\u1ee9ng polyvinyl clorua.<br><\/p>\n\n\n\n<p>T\u1ea5m polyvinyl clorua c\u1ee9ng c\u00f3 \u0111\u1ed9 trong su\u1ed1t v\u00e0 \u0111\u1ed9 b\u00f3ng t\u1ed1t. T\u1ea5m polyvinyl clorua d\u00f9ng trong bao b\u00ec d\u01b0\u1ee3c ph\u1ea9m c\u00f3 y\u00eau c\u1ea7u cao v\u1ec1 v\u1ec7 sinh nh\u1ef1a v\u00e0 ph\u1ea3i s\u1eed d\u1ee5ng nh\u1ef1a polyvinyl clorua kh\u00f4ng \u0111\u1ed9c h\u1ea1i, ch\u1ea5t bi\u1ebfn t\u00ednh kh\u00f4ng \u0111\u1ed9c h\u1ea1i v\u00e0 ch\u1ea5t \u1ed5n \u0111\u1ecbnh nhi\u1ec7t kh\u00f4ng \u0111\u1ed9c h\u1ea1i.<\/p>\n\n\n\n<p>Polyvinylidene chloride has a high molecular density, regular structure, high crystallinity, extremely strong gas sealing, excellent moisture resistance, good oil resistance, drug resistance and solvent resistance, and excellent barrier properties to oxygen, water vapor and carbon dioxide in the air. Compared with materials of the same thickness, the barrier property of polyvinylidene chloride to oxygen is 1500 times that of polyethylene, 100 times that of polypropylene, and 100 times that of polyester. It is better than polyethylene in terms of water vapor and oxygen resistance. Moreover, the sealing performance, impact strength, tensile strength and durability of polyvinylidene chloride materials can meet the special requirements of blister packaging such as medicines. <\/p>\n\n\n\n<p>Therefore, polyvinylidene chloride is one of the development directions of blister packaging materials in the future. Composite plastic sheets for drug blister packaging include PVC\/PVDC\/PE, PVDC\/OPP\/PE, PVC\/PE, etc. For drugs that require barrier properties and light protection, materials composited with plastic sheets and aluminum foil can be used, such as PET\/aluminum foil\/PP, PET\/aluminum foil\/PE composite materials.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img alt=\"vi\u00ean thu\u1ed1c\" fetchpriority=\"high\" decoding=\"async\" width=\"547\" height=\"355\" src=\"https:\/\/www.lintyco.com\/wp-content\/uploads\/2025\/03\/blister-packaging.jpg\" class=\"wp-image-72266\" srcset=\"https:\/\/www.lintyco.com\/wp-content\/uploads\/2025\/03\/blister-packaging.jpg 547w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2025\/03\/blister-packaging-300x195.jpg 300w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2025\/03\/blister-packaging-18x12.jpg 18w\" sizes=\"(max-width: 547px) 100vw, 547px\" \/><\/figure>\n\n\n\n<p><strong>(2) V\u1eadt li\u1ec7u n\u1ec1n<\/strong><\/p>\n\n\n\n<p>The substrate for blister packaging of tablets and capsules often uses coated aluminum foil. The aluminum foil is made of 99% pure electrolytic aluminum and is made by calendering. The aluminum foil has a highly dense metal crystal structure, is non-toxic and odorless, has excellent light-shielding properties, has extremely high moisture resistance, gas barrier properties and taste retention properties, and can most effectively protect the packaged items. <\/p>\n\n\n\n<p>It is widely used in drug blister packaging. The surface of the substrate should be neat and glossy, with good printability, and can be firmly coated with a heat-sealing coating to ensure that after the heat-sealing coating is melted, the substrate and the blister can be tightly combined together.<\/p>\n\n\n\n<p><strong>(3) V\u1eadt li\u1ec7u ph\u1ee7 k\u00edn nhi\u1ec7t<\/strong><\/p>\n\n\n\n<p>The heat-seal coating should be compatible with the substrate and the blister, and the heat-seal temperature should be relatively low so that it can be heat-sealed quickly without damaging the blister film. At present, the heat-seal coating materials used in pharmaceutical blister packaging are mainly divided into single-component adhesives and two-component adhesives. Single-component adhesives are mainly composed of natural rubber or synthetic rubber, nitrate cotton, and acrylic esters. They are non-drying and hot-soluble and have a certain bonding strength. <\/p>\n\n\n\n<p>Two-component adhesives are mainly polyurethane adhesives, which have good resistance to high and low temperatures, resistance to medium erosion, high adhesion, etc., and can bond multiple materials at the same time. It has been widely used in adhesives for substrate aluminum foil coating and in the composite process of various plastic films. Other commonly used heat-seal coating materials include solvent-resistant vinyl resins and water-resistant acrylic resins, both of which have good gloss, transparency and heat-sealing properties.<\/p>\n\n\n\n<p><strong>(4) M\u1ef1c in n\u1ec1n<\/strong><\/p>\n\n\n\n<p>X\u00e9t v\u1ec1 quy tr\u00ecnh in c\u1ee7a ch\u1ea5t n\u1ec1n gi\u1ea5y b\u1ea1c nh\u00f4m d\u00f9ng cho bao b\u00ec v\u1ec9 thu\u1ed1c v\u00e0 c\u00e1c y\u00eau c\u1ea7u \u0111\u1eb7c bi\u1ec7t c\u1ee7a bao b\u00ec thu\u1ed1c, m\u1ef1c in c\u1ee7a n\u00f3 ph\u1ea3i c\u00f3 \u0111\u1ed9 b\u00e1m d\u00ednh t\u1ed1t v\u1edbi gi\u1ea5y b\u1ea1c nh\u00f4m, ch\u1eef in v\u00e0 hoa v\u0103n ph\u1ea3i ch\u1eafc ch\u1eafn v\u00e0 r\u00f5 r\u00e0ng, kh\u1ea3 n\u0103ng gi\u1ea3i ph\u00f3ng dung m\u00f4i ph\u1ea3i t\u1ed1t, kh\u1ea3 n\u0103ng ch\u1ecbu nhi\u1ec7t ph\u1ea3i t\u1ed1t, kh\u1ea3 n\u0103ng ch\u1ed1ng ma s\u00e1t ph\u1ea3i tuy\u1ec7t v\u1eddi, \u0111\u1ed9 b\u00f3ng ph\u1ea3i t\u1ed1t, s\u1eafc t\u1ed1 ph\u1ea3i kh\u00f4ng \u0111\u1ed9c h\u1ea1i v\u00e0 kh\u00f4ng \u0111\u01b0\u1ee3c l\u00e0m \u00f4 nhi\u1ec5m thu\u1ed1c \u0111\u00f3ng g\u00f3i. \u0110\u1ed9 nh\u1edbt th\u1ef1c t\u1ebf ph\u1ea3i \u0111\u00e1p \u1ee9ng c\u00e1c y\u00eau c\u1ea7u quy tr\u00ecnh in gi\u1ea5y b\u1ea1c nh\u00f4m. <\/p>\n\n\n\n<p>Hi\u1ec7n nay, m\u1ef1c in d\u00f9ng cho in n\u1ec1n gi\u1ea5y nh\u00f4m ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c chia th\u00e0nh hai lo\u1ea1i: lo\u1ea1i th\u1ee9 nh\u1ea5t l\u00e0<strong>m\u1ef1c polyamide h\u00f2a tan trong c\u1ed3n.<\/strong> Since polyamide resin has good adhesion to various substances, it is especially suitable for printing polyolefin films, plus good dispersibility, good gloss and softness, good wear resistance, good solvent release and printing properties, so it is often used to prepare special plastic films. LDPE, CPP, OPP and other surface printing gravure printing inks after treatment. <\/p>\n\n\n\n<p>This kind of ink has the characteristics of good gloss, wide application, anti-adhesion, easy drying, etc., and is also used for printing aluminum foil substrate for pharmaceutical blister packaging. The second type of ink is<strong>m\u1ed9t lo\u1ea1i m\u1ef1c gi\u1ea5y nh\u00f4m \u0111\u1eb7c bi\u1ec7t<\/strong> v\u1edbi nh\u1ef1a copolymer vinyl chloride vinyl acetate v\u00e0 nh\u1ef1a acrylate l\u00e0m th\u00e0nh ph\u1ea7n ch\u00ednh. N\u00f3 c\u00f3 \u0111\u1eb7c \u0111i\u1ec3m l\u00e0 m\u00e0u s\u1eafc t\u01b0\u01a1i s\u00e1ng, n\u1ed3ng \u0111\u1ed9 cao, b\u00e1m d\u00ednh m\u1ea1nh v\u00e0o l\u00e1 nh\u00f4m, \u0111\u1ed9 trong su\u1ed1t t\u1ed1t, kh\u1ea3 n\u0103ng t\u00e1i t\u1ea1o tuy\u1ec7t v\u1eddi c\u1ee7a \u00e1nh kim c\u1ee7a l\u00e1 nh\u00f4m v\u00e0 b\u1eb1ng c\u00e1ch \u0111i\u1ec1u ch\u1ec9nh th\u00e0nh ph\u1ea7n dung m\u00f4i h\u1ed7n h\u1ee3p c\u1ee7a n\u00f3 \u0111\u1ec3 \u0111\u00e1p \u1ee9ng nhu c\u1ea7u in b\u1ec1 m\u1eb7t l\u00e1 nh\u00f4m, n\u00f3 s\u1ebd \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nhi\u1ec1u h\u01a1n trong in l\u00e1 nh\u00f4m n\u1ec1n.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Lo\u1ea1i thi\u1ebft b\u1ecb \u0111\u00f3ng g\u00f3i v\u1ec9<\/strong><\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p><strong><a href=\"https:\/\/www.lintyco.com\/vi\/packaging-equipment\/aluminum-film-blister-demo-filling-machine\/\">M\u00e1y \u0111\u00f3ng g\u00f3i v\u1ec9<\/a><\/strong> \u0111\u01b0\u1ee3c chia th\u00e0nh hai lo\u1ea1i theo m\u1ee9c \u0111\u1ed9 t\u1ef1 \u0111\u1ed9ng h\u00f3a: m\u00e1y \u0111\u00f3ng g\u00f3i b\u00e1n t\u1ef1 \u0111\u1ed9ng, m\u00e1y \u0111\u00f3ng g\u00f3i t\u1ef1 \u0111\u1ed9ng v\u00e0 d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t ho\u00e0n to\u00e0n t\u1ef1 \u0111\u1ed9ng. Vi\u1ec7c \u0111\u00f3ng g\u00f3i thu\u1ed1c (vi\u00ean n\u00e9n, vi\u00ean nang v\u00e0 thu\u1ed1c \u0111\u1ea1n, v.v.) ch\u1ee7 y\u1ebfu s\u1eed d\u1ee5ng d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t \u0111\u00f3ng g\u00f3i t\u1ef1 \u0111\u1ed9ng, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 d\u00e2y chuy\u1ec1n \u0111\u00f3ng g\u00f3i t\u1ef1 \u0111\u1ed9ng PTP (Press Through Pack). C\u00f3 hai lo\u1ea1i: ngang v\u00e0 d\u1ecdc. N\u00f3i chung, c\u1ea5u tr\u00fac nhi\u1ec1u c\u1ed9t \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng, n\u0103ng su\u1ea5t cao v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng \u0111\u00f3ng g\u00f3i t\u1ed1t. N\u00f3 \u0111\u01b0\u1ee3c trang b\u1ecb thi\u1ebft b\u1ecb ph\u00e1t hi\u1ec7n v\u00e0 c\u01a1 ch\u1ebf lo\u1ea1i b\u1ecf ch\u1ea5t th\u1ea3i, c\u00f3 th\u1ec3 k\u1ebft n\u1ed1i c\u00e1c quy tr\u00ecnh in \u1ea5n, ph\u00e2n ph\u1ed1i h\u01b0\u1edbng d\u1eabn v\u00e0 \u0111\u00f3ng h\u1ed9p v\u1edbi d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t. \u0110\u00e2y l\u00e0 d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t bao b\u00ec t\u1ef1 \u0111\u1ed9ng \u0111i\u1ec3n h\u00ecnh v\u1edbi c\u00e1c ch\u1ee9c n\u0103ng \u0111\u00f3ng g\u00f3i ho\u00e0n ch\u1ec9nh.<br><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.lintyco.com\/vi\/packaging-equipment\/aluminum-film-blister-demo-filling-machine\/https:\/\/www.lintyco.com\/packaging-equipment\/aluminum-film-blister-demo-filling-machine\/https:\/\/www.lintyco.com\/packaging-equipment\/aluminum-film-blister-demo-filling-machine\/\"><img decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-1024x1024.png\" alt=\"m\u00e1y \u0111\u00f3ng g\u00f3i v\u1ec9(1)(1)\" class=\"wp-image-16991\" srcset=\"https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-1024x1024.png 1024w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-300x300.png 300w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-150x150.png 150w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-768x768.png 768w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-1536x1536.png 1536w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-2048x2048.png 2048w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-12x12.png 12w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-600x600.png 600w, https:\/\/www.lintyco.com\/wp-content\/uploads\/2023\/11\/blister-packing-machine11-100x100.png 100w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Th\u00e0nh ph\u1ea7n c\u1ee7a thi\u1ebft b\u1ecb \u0111\u00f3ng g\u00f3i v\u1ec9<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>M\u00e1y \u0111\u00f3ng g\u00f3i v\u1ec9 thu\u1ed1c v\u1ec1 c\u01a1 b\u1ea3n gi\u1ed1ng v\u1edbi thi\u1ebft b\u1ecb \u0111\u00f3ng g\u00f3i v\u1ec9 thu\u1ed1c cho c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c v\u00e0 ch\u1ee7 y\u1ebfu bao g\u1ed3m c\u00e1c b\u1ed9 ph\u1eadn sau:<\/p>\n\n\n\n<p><strong>\u2460 Ph\u1ea7n gia nhi\u1ec7t<\/strong>. Thi\u1ebft b\u1ecb gia nhi\u1ec7t \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 l\u00e0m n\u00f3ng t\u1ea5m nh\u1ef1a, l\u00e0m m\u1ec1m n\u00f3 \u0111\u1ec3 d\u1ec5 d\u00e0ng \u0111\u00fac khu\u00f4n.<br>Theo c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ti\u1ebfp x\u00fac kh\u00e1c nhau gi\u1eefa m\u00e1y gia nhi\u1ec7t v\u00e0 t\u1ea5m m\u1ecfng, c\u00f3 hai ph\u01b0\u01a1ng ph\u00e1p gia nhi\u1ec7t: gia nhi\u1ec7t tr\u1ef1c ti\u1ebfp v\u00e0 gia nhi\u1ec7t gi\u00e1n ti\u1ebfp. Gia nhi\u1ec7t tr\u1ef1c ti\u1ebfp l\u00e0 \u0111\u1ec3 t\u1ea5m m\u1ecfng ti\u1ebfp x\u00fac v\u1edbi m\u00e1y gia nhi\u1ec7t, t\u1ed1c \u0111\u1ed9 gia nhi\u1ec7t nhanh nh\u01b0ng kh\u00f4ng \u0111\u1ec1u, th\u00edch h\u1ee3p \u0111\u1ec3 gia nhi\u1ec7t v\u1eadt li\u1ec7u m\u1ecfng h\u01a1n; gia nhi\u1ec7t gi\u00e1n ti\u1ebfp l\u00e0 s\u1eed d\u1ee5ng nhi\u1ec7t b\u1ee9c x\u1ea1 \u0111\u1ec3 gia nhi\u1ec7t g\u1ea7n t\u1ea5m m\u1ecfng, to\u00e0n di\u1ec7n v\u00e0 \u0111\u1ed3ng \u0111\u1ec1u, nh\u01b0ng t\u1ed1c \u0111\u1ed9 ch\u1eadm, th\u00edch h\u1ee3p cho c\u1ea3 v\u1eadt li\u1ec7u d\u00e0y v\u00e0 m\u1ecfng.<br>Theo c\u00e1c ngu\u1ed3n nhi\u1ec7t kh\u00e1c nhau c\u1ee7a l\u00f2 s\u01b0\u1edfi, c\u00e1c ph\u01b0\u01a1ng ph\u00e1p gia nhi\u1ec7t l\u00e0 gia nhi\u1ec7t lu\u1ed3ng kh\u00ed n\u00f3ng v\u00e0 gia nhi\u1ec7t b\u1ee9c x\u1ea1 nhi\u1ec7t. Gia nhi\u1ec7t lu\u1ed3ng kh\u00ed n\u00f3ng s\u1eed d\u1ee5ng lu\u1ed3ng kh\u00ed n\u00f3ng nhi\u1ec7t \u0111\u1ed9 cao \u0111\u1ec3 phun tr\u1ef1c ti\u1ebfp l\u00ean b\u1ec1 m\u1eb7t c\u1ee7a t\u1ea5m nh\u1ef1a m\u1ecfng \u0111\u01b0\u1ee3c gia nhi\u1ec7t. Ph\u01b0\u01a1ng ph\u00e1p n\u00e0y c\u00f3 hi\u1ec7u su\u1ea5t gia nhi\u1ec7t th\u1ea5p v\u00e0 kh\u00f4ng \u0111\u1ee7 \u0111\u1ed3ng \u0111\u1ec1u; gia nhi\u1ec7t b\u1ee9c x\u1ea1 nhi\u1ec7t s\u1eed d\u1ee5ng b\u1ee9c x\u1ea1 \u00e1nh s\u00e1ng v\u00e0 nhi\u1ec7t \u0111\u1ed9 cao do l\u00f2 s\u01b0\u1edfi h\u1ed3ng ngo\u1ea1i xa t\u1ea1o ra \u0111\u1ec3 gia nhi\u1ec7t t\u1ea5m v\u1eadt li\u1ec7u u\u1ed1n cong m\u1ecfng, c\u00f3 hi\u1ec7u su\u1ea5t gia nhi\u1ec7t cao v\u00e0 \u0111\u1ed3ng \u0111\u1ec1u.<br><\/p>\n\n\n\n<p><strong>\u2461 Ph\u1ea7n \u0111\u00fac.<\/strong> Ph\u1ea7n \u0111\u00fac c\u00f3 th\u1ec3 chia th\u00e0nh hai ph\u01b0\u01a1ng ph\u00e1p: \u0111\u00fac r\u0103ng v\u00e0 \u0111\u00fac ch\u00e2n kh\u00f4ng. \u0110\u00fac n\u00e9n l\u00e0 s\u1eed d\u1ee5ng kh\u00ed n\u00e9n \u0111\u1ec3 th\u1ed5i t\u1ea5m m\u1ecfng \u0111\u00e3 m\u1ec1m v\u00e0o khu\u00f4n sao cho g\u1ea7n v\u1edbi th\u00e0nh trong c\u1ee7a khu\u00f4n \u0111\u1ec3 t\u1ea1o th\u00e0nh v\u1ec9. Khu\u00f4n s\u1eed d\u1ee5ng h\u00ecnh d\u1ea1ng t\u1ea5m ph\u1eb3ng, th\u01b0\u1eddng \u0111\u01b0\u1ee3c truy\u1ec1n t\u1ea3i kh\u00f4ng li\u00ean t\u1ee5c ho\u1eb7c truy\u1ec1n t\u1ea3i li\u00ean t\u1ee5c. N\u00f3 c\u00f3 ch\u1ea5t l\u01b0\u1ee3ng \u0111\u00fac t\u1ed1t v\u00e0 ph\u00f9 h\u1ee3p v\u1edbi c\u1ea3 v\u1ec9 s\u00e2u v\u00e0 n\u00f4ng. \u0110\u00fac ch\u00e2n kh\u00f4ng l\u00e0 h\u1ea5p th\u1ee5 t\u1ea5m m\u1ecfng \u0111\u00e3 m\u1ec1m v\u00e0o th\u00e0nh trong c\u1ee7a khu\u00f4n \u0111\u1ec3 t\u1ea1o th\u00e0nh v\u1ec9 b\u1eb1ng c\u00e1ch h\u00fat ch\u00e2n kh\u00f4ng. Khu\u00f4n ch\u1ee7 y\u1ebfu s\u1eed d\u1ee5ng h\u00ecnh d\u1ea1ng con l\u0103n \u0111\u1ec3 truy\u1ec1n t\u1ea3i li\u00ean t\u1ee5c. Do l\u1ef1c h\u00fat do ch\u00e2n kh\u00f4ng t\u1ea1o ra b\u1ecb h\u1ea1n ch\u1ebf v\u00e0 g\u00f3c m\u00e0 v\u1ec9 r\u1eddi kh\u1ecfi con l\u0103n sau khi t\u1ea1o h\u00ecnh c\u0169ng b\u1ecb h\u1ea1n ch\u1ebf n\u00ean n\u00f3 ch\u1ec9 ph\u00f9 h\u1ee3p v\u1edbi v\u1ec9 n\u00f4ng v\u00e0 v\u1eadt li\u1ec7u m\u1ecfng h\u01a1n.<br><strong>\u2462 Thi\u1ebft b\u1ecb chi\u1ebft r\u00f3t.<\/strong> Thu\u1ed1c \u0111\u01b0\u1ee3c \u0111\u1ecbnh l\u01b0\u1ee3ng v\u00e0o v\u1ec9 \u0111\u00e3 \u0111\u1ecbnh h\u00ecnh v\u00e0 th\u01b0\u1eddng s\u1eed d\u1ee5ng thi\u1ebft b\u1ecb \u0111\u1ecbnh l\u01b0\u1ee3ng t\u1ef1 \u0111\u1ed9ng nhi\u1ec1u h\u00e0ng.<br><strong>\u2463 Thi\u1ebft b\u1ecb h\u00e0n nhi\u1ec7t.<\/strong> V\u1eadt li\u1ec7u n\u1ec1n gi\u1ea5y b\u1ea1c d\u00f9ng \u0111\u1ec3 ph\u1ee7 \u0111\u01b0\u1ee3c d\u00e1n k\u00edn tr\u00ean v\u1ec9. C\u00f3 hai lo\u1ea1i: t\u1ea5m ph\u1eb3ng v\u00e0 con l\u0103n. Lo\u1ea1i t\u1ea5m ph\u1eb3ng d\u00f9ng \u0111\u1ec3 v\u1eadn chuy\u1ec3n gi\u00e1n \u0111o\u1ea1n; lo\u1ea1i con l\u0103n d\u00f9ng \u0111\u1ec3 v\u1eadn chuy\u1ec3n li\u00ean t\u1ee5c.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Quy tr\u00ecnh s\u1ea3n xu\u1ea5t bao b\u00ec v\u1ec9<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>Quy tr\u00ecnh c\u01a1 b\u1ea3n c\u1ee7a \u0111\u00f3ng g\u00f3i v\u1ec9 l\u00e0: gia nhi\u1ec7t t\u1ea5m nh\u1ef1a, t\u1ea1o m\u00e0ng v\u00e0 do l\u00f4 s\u1ea3n xu\u1ea5t bao b\u00ec v\u1ec9 thu\u1ed1c b\u1eb1ng m\u00e1y \u0111\u00f3ng g\u00f3i v\u1ec9 l\u1edbn, ch\u1ee7ng lo\u1ea1i t\u01b0\u01a1ng \u0111\u1ed1i c\u1ed1 \u0111\u1ecbnh v\u00e0 y\u00eau c\u1ea7u an to\u00e0n v\u1ec7 sinh n\u00ean n\u00ean s\u1eed d\u1ee5ng d\u00e2y chuy\u1ec1n \u0111\u00f3ng g\u00f3i m\u00e1y \u0111\u00f3ng g\u00f3i v\u1ec9 t\u1ef1 \u0111\u1ed9ng \u0111\u1ec3 s\u1ea3n xu\u1ea5t. Trong qu\u00e1 tr\u00ecnh v\u1eadn h\u00e0nh t\u1ef1 \u0111\u1ed9ng, ngo\u00e0i vi\u1ec7c ho\u00e0n th\u00e0nh quy tr\u00ecnh \u0111\u00f3ng g\u00f3i, in \u1ea5n, l\u1eafp \u0111\u1eb7t h\u01b0\u1edbng d\u1eabn, \u0111\u00f3ng h\u1ed9p v\u00e0 c\u00e1c quy tr\u00ecnh kh\u00e1c c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c k\u1ebft n\u1ed1i v\u1edbi d\u00e2y chuy\u1ec1n \u0111\u00f3ng g\u00f3i \u0111\u1ec3 t\u1ea1o th\u00e0nh d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t bao b\u00ec v\u1ec9 ho\u00e0n to\u00e0n t\u1ef1 \u0111\u1ed9ng. Quy tr\u00ecnh s\u1ea3n xu\u1ea5t nh\u01b0 sau:<br><strong>S\u1ea3n ph\u1ea9m l\u00e0m \u0111\u1ea7y, ph\u1ee7 l\u1edbp n\u1ec1n, h\u00e0n nhi\u1ec7t, c\u1eaft v\u00e0 t\u1ec9a.<\/strong><br>(a) Cu\u1ed9n m\u00e0ng nh\u1ef1a \u0111\u01b0\u1ee3c m\u1edf ra v\u00e0 chuy\u1ec3n v\u1ec1 ph\u00eda tr\u01b0\u1edbc;<br>(b) M\u00e0ng \u0111\u01b0\u1ee3c nung n\u00f3ng v\u00e0 l\u00e0m m\u1ec1m, sau \u0111\u00f3 \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh v\u1ec9 b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p \u00e9p khu\u00f4n (s\u1eed d\u1ee5ng kh\u00ed n\u00e9n) ho\u1eb7c \u00e9p khu\u00f4n h\u00fat (s\u1eed d\u1ee5ng ch\u00e2n kh\u00f4ng) trong khu\u00f4n;<br>(c) S\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c n\u1ea1p b\u1eb1ng c\u01a1 ch\u1ebf n\u1ea1p t\u1ef1 \u0111\u1ed9ng;<br>(d) Ph\u00e1t hi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng c\u1ee7a khu\u00f4n v\u00e0 chi\u1ebft v\u1ec9. Trong d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t t\u1ef1 \u0111\u1ed9ng, th\u01b0\u1eddng s\u1eed d\u1ee5ng m\u00e1y d\u00f2 quang \u0111i\u1ec7n. Khi ph\u00e1t hi\u1ec7n s\u1ea3n ph\u1ea9m kh\u00f4ng \u0111\u1ea1t y\u00eau c\u1ea7u, t\u00edn hi\u1ec7u l\u1ed7i \u0111\u01b0\u1ee3c g\u1eedi \u0111\u1ebfn thi\u1ebft b\u1ecb b\u1ed9 nh\u1edb. Sau khi qu\u00e1 tr\u00ecnh \u0111\u1ed9t d\u1eadp ho\u00e0n t\u1ea5t, s\u1ea3n ph\u1ea9m l\u1ed7i s\u1ebd t\u1ef1 \u0111\u1ed9ng \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf;<br>(e) V\u1eadt li\u1ec7u n\u1ec1n cu\u1ed9n \u0111\u01b0\u1ee3c ph\u1ee7 tr\u00ean v\u1ec9 \u0111\u00e3 \u0111\u1ed5 \u0111\u1ea7y;<br>(f) V\u1ec9 v\u00e0 ch\u1ea5t n\u1ec1n \u0111\u01b0\u1ee3c d\u00e1n k\u00edn v\u1edbi nhau b\u1eb1ng m\u00e1y h\u00e0n nhi\u1ec7t d\u1ea1ng t\u1ea5m ho\u1eb7c d\u1ea1ng con l\u0103n;<br>(g) S\u1ed1 l\u00f4 v\u00e0 ng\u00e0y s\u1ea3n xu\u1ea5t \u0111\u01b0\u1ee3c in \u1edf m\u1eb7t sau c\u1ee7a ch\u1ea5t n\u1ec1n;<br>(h) \u0110\u1ee5c v\u00e0o t\u1eebng \u0111\u01a1n v\u1ecb \u0111\u00f3ng g\u00f3i. Sau khi qu\u00e1 tr\u00ecnh \u0111\u1ee5c ho\u00e0n t\u1ea5t, thi\u1ebft b\u1ecb lo\u1ea1i b\u1ecf l\u1ed7i s\u1ebd lo\u1ea1i b\u1ecf c\u00e1c s\u1ea3n ph\u1ea9m l\u1ed7i theo t\u00edn hi\u1ec7u \u0111\u01b0\u1ee3c l\u01b0u tr\u1eef trong thi\u1ebft b\u1ecb b\u1ed9 nh\u1edb.<br>(j) C\u00e1c h\u01b0\u1edbng d\u1eabn v\u00e0 h\u1ed9p \u0111\u01b0\u1ee3c l\u1eafp \u0111\u1eb7t \u0111\u1ec3 tr\u1edf th\u00e0nh g\u00f3i b\u00e1n h\u00e0ng.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ph\u1ea7n k\u1ebft lu\u1eadn<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>\u0110\u00f3ng g\u00f3i v\u1ec9 thu\u1ed1c l\u00e0 m\u1ed9t quy tr\u00ecnh quan tr\u1ecdng \u0111\u1ea3m b\u1ea3o t\u00ednh an to\u00e0n, b\u1ea3o v\u1ec7 v\u00e0 to\u00e0n v\u1eb9n c\u1ee7a thu\u1ed1c. B\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng c\u00e1c v\u1eadt li\u1ec7u ch\u1ea5t l\u01b0\u1ee3ng cao nh\u01b0 polyvinyl clorua, polyvinylidene clorua v\u00e0 gi\u1ea5y b\u1ea1c, c\u00f9ng v\u1edbi thi\u1ebft b\u1ecb t\u1ef1 \u0111\u1ed9ng hi\u1ec7u qu\u1ea3, quy tr\u00ecnh \u0111\u00f3ng g\u00f3i v\u1ec9 thu\u1ed1c kh\u00f4ng ch\u1ec9 \u0111\u00e1p \u1ee9ng c\u00e1c ti\u00eau chu\u1ea9n v\u1ec7 sinh v\u00e0 an to\u00e0n nghi\u00eam ng\u1eb7t m\u00e0 c\u00f2n cung c\u1ea5p kh\u1ea3 n\u0103ng b\u1ea3o v\u1ec7 r\u00e0o c\u1ea3n n\u00e2ng cao ch\u1ed1ng l\u1ea1i \u0111\u1ed9 \u1ea9m, \u00e1nh s\u00e1ng v\u00e0 kh\u00f4ng kh\u00ed. Quy tr\u00ecnh s\u1ea3n xu\u1ea5t, t\u1eeb gia nhi\u1ec7t v\u00e0 t\u1ea1o h\u00ecnh t\u1ea5m nh\u1ef1a \u0111\u1ebfn chi\u1ebft r\u00f3t v\u00e0 h\u00e0n nhi\u1ec7t, \u0111\u1ea3m b\u1ea3o gi\u1ea3i ph\u00e1p \u0111\u00f3ng g\u00f3i \u0111\u00e1ng tin c\u1eady v\u00e0 an to\u00e0n cho c\u00e1c s\u1ea3n ph\u1ea9m d\u01b0\u1ee3c ph\u1ea9m. Khi ng\u00e0nh c\u00f4ng nghi\u1ec7p ti\u1ebfp t\u1ee5c ph\u00e1t tri\u1ec3n, s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c v\u1eadt li\u1ec7u v\u00e0 c\u00f4ng ngh\u1ec7 \u0111\u00f3ng g\u00f3i ti\u00ean ti\u1ebfn s\u1ebd c\u1ea3i thi\u1ec7n h\u01a1n n\u1eefa hi\u1ec7u qu\u1ea3 v\u00e0 t\u00ednh b\u1ec1n v\u1eefng c\u1ee7a bao b\u00ec v\u1ec9 thu\u1ed1c, khi\u1ebfn n\u00f3 tr\u1edf th\u00e0nh l\u1ef1a ch\u1ecdn kh\u00f4ng th\u1ec3 thi\u1ebfu trong ng\u00e0nh d\u01b0\u1ee3c ph\u1ea9m.<\/p>","protected":false},"excerpt":{"rendered":"<p>Kh\u00e1m ph\u00e1 nh\u1eefng \u0111i\u1ec1u c\u1ea7n thi\u1ebft v\u1ec1 bao b\u00ec v\u1ec9 d\u01b0\u1ee3c ph\u1ea9m, bao g\u1ed3m c\u00e1c v\u1eadt li\u1ec7u ch\u00ednh nh\u01b0 PVC v\u00e0 gi\u1ea5y b\u1ea1c, thi\u1ebft b\u1ecb ti\u00ean ti\u1ebfn nh\u01b0 d\u00e2y chuy\u1ec1n \u0111\u00f3ng g\u00f3i t\u1ef1 \u0111\u1ed9ng v\u00e0 quy tr\u00ecnh t\u1eebng b\u01b0\u1edbc chi ti\u1ebft \u0111\u1ec3 \u0111\u00f3ng g\u00f3i hi\u1ec7u qu\u1ea3 v\u00e0 an to\u00e0n.<\/p>","protected":false},"author":1,"featured_media":17250,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_titles_title":"Pharmaceutical Blister Packaging Guide: Materials, Equipment, Process | Lintyco","_seopress_titles_desc":"Pharmaceutical blister packaging guide covering PVC, aluminum foil, and barrier materials. 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